Abstract
Background: Intravenous regional anesthesia (IVRA) is an ideal technique for short surgery on the distal extremities. Different additives have been used to improve lidocaine’s block quality. 
Objective: The aim of this study was to determine the effect of adding dexamethasone to lidocaine on improving the quality of IVRA.
Methods: This study is a prospective, double-blind randomized study which was done on patients with upper extremity injuries of the distal elbow in Shahid Mohammadi Hospital, Bandar Abbas from October 2014 to December 2015. A total of 110 patients aged 15 to 65 years, with ASA class I and II, with orthopedic injuries distal to the elbow, were randomly divided into two groups. The control group (L) and the intervention group (L+D) received a 40-ml solution of 3 mg/kg lidocaine, and 3 mg/kg lidocaine + 8 mg of dexamethasone respectively. The two groups were compared in terms of onset and recovery time of sensory block in each of the dermatome nerves classified as radial, ulnar, and median, vital signs, patient satisfaction, intraoperative opioid consumption, and request for the first postoperative opioid.
Results: There was no significant difference between the two groups in terms of demographic characteristics. Mean arterial blood pressure was higher in the L + D group (100.39±14.6 mmHg) in comparison to the L group (90.50±11 mmHg) (p=0.002). Need for opioid was reported in 20 (35.7%) patients in the L + D group in comparison to 17 (31.5%) in the L group (p=0.639). The average intraoperative dose of fentanyl was 95±32.04 mcg and 88.44±18.77 mg in L + D and L groups respectively and there was no significant difference between the two groups in this respect (p=0.479). In addition, the average dose of pethidine administered in the recovery room for L + D group (19.34±15.22) mg was significantly higher than in the L group (9.44±12.26 mg) (p=0.001).
Conclusions: Adding 8 mg dexamethasone to lidocaine has no effect on IVRA solution in upper extremity orthopedic operations and also increases postoperative opioid consumption.
Trial registration: The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the Irct ID: IRCT2016052928158N1.
Funding: The authors received financial support from Hormozgan University of Medical Sciences.

 

 
Keywords: Lidocaine, Additive, Dexamethasone, Upper extremity

 

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Volume 12, issue 1, January-March 2020


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In April-June 2020 issue, the journal will publish an editorial from Morocco (Dr. Benksim, Higher Institute of Nursing Professions and Health Techniques, Morocco). The editorial talks about lessons from COVID-19 pandemic and the Morocco’s success story. The April-June issue is expected to be published by end of June 2020.


 

The worldwide spread of COVID-19 as an emerging, rapidly evolving situation, and the dramatic need of urgent medicine or vaccine, has rapidly brought new hypotheses for pathophysiology and potential medicinal agents to the fore. It is crucial that the research community provide a way to publish this research in a timely manner.

To contribute to this important public health discussion, the Electronic Physician Journal is excited to announce a fast-track procedure to help researchers publish their articles on COVID-19 related subjects that fall under the broad definition of public health, internal medicine, and pharmacology. We are especially welcome to all hypotheses about the pathological basis of the COVID-19 infection and the possible characteristics of potential medicine and vaccine. Submit your manuscript here


 

The 6th World Conference on Research Integrity (WCRI) is to be held on June 2-5, 2019 in Hong Kong.

The WCRI is the largest and most significant international conference on research integrity. Since the first conference in Lisbon in 2007, it has given researchers, teachers, funding agencies, government officials, journal editors, senior administrators, and research students opportunities to share experiences and to discuss and promote integrity in research. Read more:


 

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Meta-Analysis Workshops in New York, USA, and London, UK, in April and May 2019

Don't miss this exceptional opportunity to learn how to perform and report a Meta-analysis correctly. Two Meta-analysis workshops are organized in April and May 2019 by Dr. Michael Borenstein in New York, USA (April 08-10, 2019) and London, UK (May 27-29).

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