Introduction: Colorectal cancer commonly metastasizes to the liver. Patients treated by metastasectomy gain a longer overall survival and progression-free survival than those patients treated by radiofrequency ablation. 
Case presentation: This paper reports the case of a 58-year-old male who presented with constipation, bleeding per rectum and weight loss. Colonoscopy showed rectosigmoid mass, and an MRI of the abdomen and pelvis revealed that there was a circumferential polypoidal rectal soft tissue mass involving the upper half of the rectum extending approximately 8 cm in the longitudinal length to the retro-sigmoid junction and 9 cm from the anal verge. It showed local extension to the mesorectal fat with significant invasion to the mesorectal fascia anteriorly. The lesion did not extend to the scrotum, prostate or urinary bladder. Multiple mesorectal lymph node and multiple foci lesions were seen in the liver, suggesting metastasis. The patient was staged as T3N2M1. After that, lower anterior resection with diversion ileostomy and intraoperative radiofrequency ablation of segment IVa and resection of IVb segment was done. From 2013 to 2017 the patient had multiple procedures: right hepatectomy, resection of segment II and IVA, alcohol ablation of segment II, microwave ablation through US guided for segment II and wedge resection in segment IV respectively. Six weeks later, the patient was looking well with normal liver function tests. Resection offers the greatest possibility of cure for patients with liver-isolated colorectal cancers, with 5-year survival rates of 25-58%. 
Take-away lesson: The overall clinical importance of this case report is to show how repeated liver resection improves the quality of life.
Keywords: Colorectal cancer, Liver, Metastasis, Recurrences


» HTML Fulltext    » PDF Fulltext    » doi: 10.19082/7364

Current Issue

July-September 2019 (Volume 11, Issue 3)


Previous Issue

In the second issue of the journal Electronic Physician for 2019, we have several papers including four Randomized Controlled Trials, a model development study, a case report, an editorial, a letter to editor (LTE), and several original research including two studies with qualitative approach. Authors of this issue are from nine countries: Iran, The Netherlands, Sweden, Italy, India, Thailand, Saudi Arabia, United Arab Emirates (UAE), and Jordan. Read more...


The 6th World Conference on Research Integrity (WCRI) is to be held on June 2-5, 2019 in Hong Kong.

The WCRI is the largest and most significant international conference on research integrity. Since the first conference in Lisbon in 2007, it has given researchers, teachers, funding agencies, government officials, journal editors, senior administrators, and research students opportunities to share experiences and to discuss and promote integrity in research. Read more:


TDR Clinical Research and Development Fellowships

Call for applications

Deadline for submission: 7 March 2019, 16:00 (GMT)

TDR provides fellowships for early- to mid-career researchers and clinical trial staff (e.g. clinicians, pharmacists, medical statisticians, data managers, other health researchers) in low- and middle-income countries (LMICs) to learn how to conduct clinical trials. Read more:

Meta-Analysis Workshops in New York, USA, and London, UK, in April and May 2019

Don't miss this exceptional opportunity to learn how to perform and report a Meta-analysis correctly. Two Meta-analysis workshops are organized in April and May 2019 by Dr. Michael Borenstein in New York, USA (April 08-10, 2019) and London, UK (May 27-29).

About the Instructor

Dr. Michael Borenstein, one of the authors of Introduction to Meta-Analysis, is widely recognized for his ability to make statistical concepts accessible to researchers as well as to statisticians. He has lectured widely on meta-analysis, including at the NIH, CDC, and FDA. Read more: